The Alex M. Glockner Hardware Company was located on Gallia and Gay streets. In the 1900 City Directory, it says the address was 206 Market and 135 West Streets.
Hibbs Hardware was located was located on Sixth (6th) Street across from the old stone post office. Hibbs closed about 1990.
The All Saints Episcopal Church was located at 610 Fourth (4th) Street. The church was built in 1850.
Hempstead Hospital was located on Chillicothe Street at the northcorner of Kinney's Lane. It was later known as the General Hospital.
Opened in 1898 at Chillicothe and Third (3rd) Streets, the Anderson Brothers Company first was a home factory shoe store, but later they added dry goods. In 1925 the two top floors were added to the Anderson Brothers Department Store building. From 1935 to 1984 the building was home to Sears, Roebuck & Company. After Sears closed it was remodeled into the Park apartments.
The Biggs House was built at the corner of Front and Market Streets. In 1980, it became part of the Riverview Retirement Center along with the Washington Hotel. The main entrance of the Biggs House now faces the courtyard shared with the Washington and its side doors are on 445 Front Street.
In 1889, the Breece Manufacturing Company was located on the east end of Portsmouth near the N & W terminal yards and the Ohio River. They made table rims, veneer tops, panels, chair backs, carriage and automobile rims and spokes, and other furniture.
The Brodt Shoe Company was located at 519-527 Front Street.
The Tracy Shoe Company was located at 630-632 2nd (Second) Street.
Both manufactured wholesale shoes.
