Kidz Biz was located in the old building that was used by Bragdon's Dry Goods Store (409 Chillicothe) in the early 1900s. It closed in 1967. CVS (newer structure) was located where Haas Men's Clothing Store and a drug store were in the early 1900s (buildings torn down for CVS). The building now houses the DollarTree (2023).
The George D. Scudder School was built in 1929. It was considered a "modern platoon style" school with a gym, cafeteria, and separate areas for classrooms. George Drake Scudder was a prominent Portsmouth resident, attorney and school board member.
The school closed in 1973. The building was used for various Portsmouth City School and Scioto County Schools Administration offices for many years. The building was often referred to as the Scudder Administrative Center.
In 1892, the Schloss Brothers & Company, stationers, was listed in the city directory. From 1918 to 1919, the building was Curtis & Shumway, and 1920s, it was Liberty Confectionary/Cafe. It has been used for various commercial businesses including a fuel company.
Earliest listing for 416 Chillicothe is in 1892 as T. Schiff, salvage store. Next listing is in 1913-14, as the London Shop Men's Clothing. From 1914 to 1926, the Si Strauss & Company. Merit Shoes moved in in 1930, replacing the Princess Shoppe. In the 1940s, the Modern Shop, Collins Store until 1968, when Artwill opened.
Listings for 418 Chillicothe include: Henry Ruel market, 1908; Sugar Bowl , 1910; Senate Cafe; Bake Shop, 1920s, Artwil, 1930s-60s; The Book Rack, 1970s
Listed in 1894 as Laubley & Son Saloon, in 1898 as Jacob Linck Saloon & Billiard Hall/ Roth Sporting Goods.
In 1921, it was the home of Queen City Restaurant. From 1937 onward, it has been used for various commercial stores.